Characterization of a V3 domain-specific neutralizing human monoclonal antibody that preferentially recognizes non-syncytium-inducing human immunodeficiency virus type 1 strains.

doi:10.1099/0022-1317-76-7-1665

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Article

Characterization of a V3 domain-specific neutralizing human monoclonal antibody that preferentially recognizes non-syncytium-inducing human immunodeficiency virus type 1 strains.

The Journal of general virology - 1 Jul 1995

Schutten M, Langedijk J P, Andeweg A C, Huisman R C, Meloen R H, Osterhaus A D

Abstract excerpt

A type-specific human immunodeficiency virus type 1 (HIV-1)-neutralizing human monoclonal antibody (HuMAb MN215) is described that reacts with the V3 domain of a number of subtype B virus strains. Pepscan analysis indicated that amino acids at both sides of the tip of the V3 loop were involved in...

Topics

Amino Acid Sequence
Amino Acids
Antibodies, Monoclonal
B-Lymphocytes
Binding Sites, Antibody
Cell Line
Cross Reactions
Epitopes
Glycoproteins
HIV-1
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Neutralization Tests

Peptides

Phenotype

Protein Structure, Tertiary

Species Specificity

Source

Open in PubMed

Identifiers

PMID: 9049372
DOI: 10.1099/0022-1317-76-7-1665

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9049372-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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