Article
Characterization of a V3 domain-specific neutralizing human monoclonal antibody that preferentially recognizes non-syncytium-inducing human immunodeficiency virus type 1 strains.
The Journal of general virology - 1 Jul 1995
Schutten M, Langedijk J P, Andeweg A C, Huisman R C, Meloen R H, Osterhaus A D
Abstract excerpt
A type-specific human immunodeficiency virus type 1 (HIV-1)-neutralizing human monoclonal antibody (HuMAb MN215) is described that reacts with the V3 domain of a number of subtype B virus strains. Pepscan analysis indicated that amino acids at both sides of the tip of the V3 loop were involved in the binding of HuMAb MN215. The minimum epitope in a V3 sequence, obtained from the donor from whom the cell line...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.