Article

Pulmonary mRNA-LNP Vaccines for Rapid and Durable Protection Against Bacterial Infection

2025-12-21

Abstract excerpt

Pulmonary bacterial infections remain a major clinical challenge. Although vaccination reduces infection rates and mortality, the vulnerable post-vaccination immunity gap can still result in infection and vaccine failure. In addition, effective vaccines are unavailable for many clinically important bacterial pathogens. Here, we report a pulmonary mRNA-lipid nanoparticle (mRNA-LNP) vaccine incorporating a novel ion...

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Literature Corpus work: acb2e453-dc39-598a-a7a2-b64f1ebe8054
DOI: 10.64898/2025.12.19.695407

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