Article

Systemic trafficking of mRNA lipid nanoparticle vaccine following intramuscular injection generates potent tissue-specific T cell response

2025-04-24

Abstract excerpt

The mRNA lipid nanoparticles (LNPs) represent a new generation of vaccine carriers designed to elicit potent immune responses against infectious diseases and cancer. Despite the clinical success and rapid advancements in mRNA LNP technologies, the trafficking patterns of LNPs after intramuscular (i.m.) administration and the subsequent tissue-specific immunological effects have not been systematically characterize...

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Literature Corpus work: 28f2f4ac-399f-5b29-85f7-8a6e8f47d40a
DOI: 10.1101/2025.04.21.649878

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