Article

Mitochondrial Variants of Complex I Genes as Potential Biomarkers to Leprosy

2023-11-08

Abstract excerpt

<h4>Background: </h4> Leprosy is a chronic bacterial infection mainly caused by Mycobacterium leprae that primarily affects skin and peripheral nerves. Due to its ability to absorb carbon from the host cell, the bacillus became dependent on energy production, mainly through oxidative phosphorylation. In fact, variations in genes of Complex I of oxidative phosphorylation encoded by mtDNA have been associated with s...

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Literature Corpus work: acaf04f0-27ff-5f0b-8fd9-be9710574e46
DOI: 10.21203/rs.3.rs-3524342/v1

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