Article

Whole Mitogenome Sequencing Uncovers a Relation Between Mitochondrial Heteroplasmy and Leprosy Severity

2023-11-08

Abstract excerpt

<h4>Background: </h4> In recent years, a mitochondria/immune system interaction has been proposed, so that variants of mitochondrial genome and levels of heteroplasmy might deregulate important metabolic processes in fighting infections, such as leprosy. We sequenced the whole mitochondrial genome to investigate variants and heteroplasmy levels, considering patients with different clinical forms of leprosy and hou...

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Literature Corpus work: 6a48f9ca-e6fa-5076-9938-a297327c874a
DOI: 10.21203/rs.3.rs-3462961/v2

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