Article
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
2021-04-08
Abstract excerpt
An ideal anti-SARS-CoV-2 antibody would resist viral escape 1–3 , have activity against diverse SARS-related coronaviruses 4–7 , and be highly protective through viral neutralization 8–11 and effector functions 12,13 . Understanding how these properties relate to each other and vary across epitopes would aid development of antibody therapeutics and guide vaccine design. Here, we comprehensively characterize es...
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Identifiers and source
- Literature Corpus work
- ac79fc54-1030-5972-b21d-bd744bb0d174
- DOI
- 10.1101/2021.04.06.438709
