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Article

Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape

2021-04-08

Abstract excerpt

An ideal anti-SARS-CoV-2 antibody would resist viral escape 1–3 , have activity against diverse SARS-related coronaviruses 4–7 , and be highly protective through viral neutralization 8–11 and effector functions 12,13 . Understanding how these properties relate to each other and vary across epitopes would aid development of antibody therapeutics and guide vaccine design. Here, we comprehensively characterize es...

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Identifiers and source

Literature Corpus work
ac79fc54-1030-5972-b21d-bd744bb0d174
DOI
10.1101/2021.04.06.438709
Open publication

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Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escapeDOI 10.1101/2021.04.06.438709
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