Article

Cytoarchitectonic gradients of laminar degeneration in behavioral variant frontotemporal dementia

2024-04-09

Abstract excerpt

<h4>ABSTRACT</h4> Behavioral variant frontotemporal dementia (bvFTD) is a clinical syndrome primarily caused by either tau (bvFTD-tau) or TDP-43 (bvFTD-TDP) proteinopathies. We previously found lower cortical layers and dorsolateral regions accumulate greater tau than TDP-43 pathology; however, patterns of laminar neurodegeneration across diverse cytoarchitecture in bvFTD is understudied. We hypothesized that bvF...

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Literature Corpus work: ac2e447a-32ac-5f10-9586-f2e8f5b4c657
DOI: 10.1101/2024.04.05.588259

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