Article

High-plex Digital Spatial Profiling Identifies Subregion-Dependent Directed Proteome Changes Across Multiple Variants of Dementia

2024-05-01

Abstract excerpt

<h4>ABSTRACT</h4> Frontotemporal lobar degeneration (FTLD) is the leading cause of dementia in patients under the age of 65. Even in a single anatomical region, there is variance within pathological protein deposition as a result of FTLD. This spectrum of pathology leads to difficulty in identification of the disease during its progression and consequential varied post mortem clinicopathological diagnoses. NanoSt...

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Literature Corpus work: bf5b20da-c7dc-508c-93ec-8fc730d4594a
DOI: 10.1101/2024.04.29.591721

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