Article
Machine Learning Classification of Alzheimer’s Disease Pathology Reveals Diffuse Amyloid as a Major Predictor of Cognitive Impairment in Human Hippocampal Subregions
2023-06-05
Abstract excerpt
Analyzing Alzheimer’s disease (AD) pathology within anatomical subregions is a significant challenge, often carried out by pathologists using a standardized, semi-quantitative approach. To augment traditional methods, a high-throughput, high-resolution pipeline was created to classify the distribution of AD pathology within hippocampal subregions. USC ADRC post-mortem tissue sections from 51 patients were stained...
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Identifiers and source
- Literature Corpus work
- 7f7b612f-2a8e-58bd-87fd-e0efc1e80529
- DOI
- 10.1101/2023.05.31.543117
