Article

Alzheimer’s disease clinical variants show distinct regional patterns of neurofibrillary tangle accumulation

2019-02-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Neurofibrillary tangle (NFT) pathology in Alzheimer’s disease (AD) follows a stereotypic progression well-characterized by Braak staging. However, some AD cases show deviations from the Braak staging scheme. In this study, we tested the hypothesis that these variations in the regional distribution of tau pathology are linked to heterogeneity in the clinical phenotypes of AD....

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Literature Corpus work: e5b7c32b-c08a-5d2d-8e0a-0faa83e4cfac
DOI: 10.1101/538496

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