Back to search

Article

Why do we die? Uncovering the genetic connections causing COVID-19 disease severity 

2020-06-04

Abstract excerpt

<title>Abstract</title> <p>SARS-CoV-2 attacks randomly causing deaths among certain populations. Additionally, this disease seems to kill males preferentially. This study investigates why by examining single nucleotide polymorphisms (SNPs) correlated with increased protein expression associated with viral infection of cells leading to disease proliferation. ACE2, the assumed host cell receptor for the virus is be...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ac1dd447-1110-5a1c-9a11-52a5ce6dad8f
DOI
10.21203/rs.3.rs-33174/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Why do we die? Uncovering the genetic connections causing COVID-19 disease severity&nbsp;DOI 10.21203/rs.3.rs-33174/v1
ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease.Semantic proximity
The Expression and Polymorphism of Entry Machinery for COVID-19 in Human: Juxtaposing Population Groups, Gender, and Different TissuesSemantic proximity
ACE2, TMPRSS2, and TLR8 single-nucleotide polymorphisms are associated with a high risk of severe COVID-19 disease and deathSemantic proximity
ACE2 and COVID-19 Susceptibility and SeveritySemantic proximity
ACE2 polymorphisms as potential players in COVID-19 outcomeSemantic proximity
The Expression and Polymorphism of Entry Machinery for COVID-19 in Human: Juxtaposing Population Groups, Gender, and Different TissuesSemantic proximity
Identifying Pathways and Networks Associated With the SARS-CoV-2 Cell Receptor ACE2 Based on Gene Expression Profiles in Normal and SARS-CoV-2-Infected Human TissuesSemantic proximity
SARS‐CoV ‐2 multifaceted interaction with the human host. Part II : Innate immunity response, immunopathology, and epigeneticsSemantic proximity
Genome-wide analysis in 756,646 individuals provides first genetic evidence that <i>ACE2</i> expression influences COVID-19 risk and yields genetic risk scores predictive of severe diseaseSemantic proximity
ACE2, TMPRSS2, TYK2, SLC6A20, and IFNAR2 human genes variants influence SARS‑CoV‑2 infection susceptibilitySemantic proximity
Age is Associated With Increased Expression of Pattern Recognition Receptor Genes and ACE2, the Receptor for SARs-Cov-2:&nbsp;Implications for the Epidemiology of COVID-19 DiseaseSemantic proximity
Assessing COVID-19 Susceptibility Through Analysis of the Genetic and Epigenetic Diversity of ACE2-Mediated SARS-CoV-2 EntrySemantic proximity
Select a neighboring publication to make it the new centre.