Article

ACE2, TMPRSS2, and TLR8 single-nucleotide polymorphisms are associated with a high risk of severe COVID-19 disease and death

2025-12-17

Abstract excerpt

Several studies have shown that genetic factors influence severity and susceptibility to COVID-19. We assessed the impact of single nucleotide polymorphisms (SNPs) in genes involved in SARS-CoV-2 entry and innate immune signaling as risk factors to COVID-19 critical outcomes, such as mechanical ventilation support (MVS) and/or death. The study included 384 inpatients from the Hospital Center for COVID-19 (INI/FIOC...

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Literature Corpus work: a87fca11-f538-5127-9cf7-98b62982e232
DOI: 10.22541/au.176599279.98135544/v1

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