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Age is Associated With Increased Expression of Pattern Recognition Receptor Genes and ACE2, the Receptor for SARs-Cov-2: Implications for the Epidemiology of COVID-19 Disease

2020-09-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Older aged adults and those with pre-existing conditions are at highest risk for severe COVID-19 associated outcomes. <bold>Methods: </bold>Using a large dataset of genome-wide RNA-seq profiles derived from human dermal fibroblasts (GSE113957) we investigated whether age affects the expression of pattern recognition receptor (PRR) genes and <italic>ACE2, </itali...

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Literature Corpus work
6656b847-880e-5432-969b-615436ab9fac
DOI
10.21203/rs.3.rs-66772/v1
Open publication

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Age is Associated With Increased Expression of Pattern Recognition Receptor Genes and ACE2, the Receptor for SARs-Cov-2:&nbsp;Implications for the Epidemiology of COVID-19 DiseaseDOI 10.21203/rs.3.rs-66772/v1
AGE IS ASSOCIATED WITH INCREASED EXPRESSION OF PATTERN RECOGNITION RECEPTOR GENES AND <i>ACE2</i> , THE RECEPTOR FOR SARS-COV-2: IMPLICATIONS FOR THE EPIDEMIOLOGY OF COVID-19 DISEASESemantic proximity
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