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Assessing COVID-19 Susceptibility Through Analysis of the Genetic and Epigenetic Diversity of ACE2-Mediated SARS-CoV-2 Entry

27 Nov 2020

Abstract excerpt

There is considerable variation in disease course among individuals infected with SARS-CoV-2. Many of them do not exhibit any symptoms, while some others proceed to develop COVID-19; however, severity of COVID-19 symptoms greatly differs among individuals. Focusing on the early events related to SARS-CoV-2 entry to cells through the ACE2 pathway, we describe how variability in (epi)genetic factors can conceivably...

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PMID: 33243086
DOI: 10.2217/pgs-2020-0092

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