Article
ACE2 and TMPRSS2 polymorphisms in various diseases with special reference to its impact on COVID-19 disease.
Microbial pathogenesis - 1 Jan 2021
Singh HariOm, Choudhari Ranjana, Nema Vijay, Khan Abdul Arif
Abstract excerpt
BACKGROUND: A carboxypeptidase protein called ACE2 is found in many organs. ACE2 protein can play a pivotal role to regulate the pathological changes of several diseases including COVID-19. TMPRSS2 gene is expressed in many human tissues and plays a critical role in spreading the infection of the viruses including coronavirus and progression of prostate cancer, and hence could be used as a potential drug target....
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