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ACE2 and COVID-19 Susceptibility and Severity

1 Jan 2022

Abstract excerpt

Sick, male, and older populations are more vulnerable to COVID-19. However, it remains unclear whether a common mechanism exists across different demographic characteristics. SARS-CoV-2 infection is initiated by the specific binding of the viral spike protein to angiotensin-converting enzyme 2 (ACE2). This study analyzed the demographics of pulmonary ACE2 expression, Mendelian randomization (MR) of ACE2 and...

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PMID: 35371596
DOI: 10.14336/ad.2021.0805

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