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Data-driven modelling of tau pathology reveals distinct progressive supranuclear palsy subtypes

2025-08-05

Abstract excerpt

Progressive supranuclear palsy (PSP) is a heterogeneous neurodegenerative disease characterised by the accumulation of misfolded 4-repeat tau within neurones and glial cells. There is limited longitudinal data on pathologically confirmed PSP patients with phenotypes other than classical Richardson’s syndrome (RS), and the pathomechanisms responsible for the broad variability in clinical phenotype and progression a...

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Literature Corpus work
d699be4d-f6e2-58a2-93d4-17121e87f725
DOI
10.1101/2025.08.03.25332866
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Data-driven modelling of tau pathology reveals distinct progressive supranuclear palsy subtypesDOI 10.1101/2025.08.03.25332866
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