Article

Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues

2023-11-02

Abstract excerpt

<h4>SUMMARY</h4> Metastasis is a leading cause of cancer-related deaths, yet understanding how metastatic tumors adapt from their origin to target tissues is challenging. To address this, we assessed whether primary and metastatic tumors resemble their tissue of origin or target tissue in terms of gene expression. We analyzed gene expression profiles from various cancer types, including single-cell and bulk RNA-s...

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Literature Corpus work: a30cf6b0-9087-5743-8433-2381a8a43d42
DOI: 10.1101/2023.10.30.564810

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