Article

Integrating microarray-based spatial transcriptomics and single-cell RNA-sequencing reveals tissue architecture in oesophageal squamous cell carcinoma

2022-04-14

Abstract excerpt

<h4>Background: </h4> The tumour microenvironment (TME) serves as an important factor in tumorigenesis and metastasis. Although distinct cell subsets can be identified via single-cell RNA sequencing (scRNA-seq), the spatial composition of cells within the TME is difficult to characterise. Methods Tissue samples were collected from three patients with oesophageal squamous cell carcinoma (ESCC), and scRNA-seq was p...

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Literature Corpus work: 63357d17-2473-5b29-9013-1370c0aebd76
DOI: 10.21203/rs.3.rs-1539014/v1

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