Article

Targeting <i>Runx</i> 1 protects against heart failure with preserved ejection fraction

2025-01-27

Abstract excerpt

<h4>ABSTRACT</h4> Heart failure with preserved ejection fraction (HFpEF) is a public health problem and an elusive illness for which there are few treatment options. HFpEF is a systemic condition with a broad phenotype including diastolic dysfunction, pulmonary oedema, exercise intolerance, and left ventricular (LV) hypertrophy, collectively resulting in enhanced morbidity and mortality. Master-regulator transcri...

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Literature Corpus work: abdf3087-96d0-5a01-b388-e2f3fad57973
DOI: 10.1101/2025.01.24.634831

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