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Article

RUNX1: an emerging therapeutic target for cardiovascular disease

3 Feb 2020

Abstract excerpt

Runt-related transcription factor-1 (RUNX1), also known as acute myeloid leukaemia 1 protein (AML1), is a member of the core-binding factor family of transcription factors which modulate cell proliferation, differentiation, and survival in multiple systems. It is a master-regulator transcription factor, which has been implicated in diverse signalling pathways and cellular mechanisms during normal development and...

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PMID: 32154891
DOI: 10.1093/cvr/cvaa034

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