Article

White-box Deep Neural Network Prediction of Genome-Wide Transcriptome Signatures

2021-02-12

Abstract excerpt

Prediction algorithms for protein or gene structures, including transcription factor binding from sequence information, have been transformative in understanding gene regulation. Here we ask whether human transcriptomic profiles can be predicted solely from the expression of transcription factors (TFs). To this end, we explore whether a neural network (NN) could predict the transcriptome from TFs. Using at least o...

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Literature Corpus work: 0b957e0c-6f63-5326-958a-8e4ed2e0b401
DOI: 10.1101/2021.02.11.430730

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