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Machine Learning–Guided Differentiation Therapy Targets Cancer Stem Cells in Colorectal Cancers

2023-09-17

Abstract excerpt

Despite advances in artificial intelligence (AI) within cancer research, its application toward realizing differentiation therapy in solid tumors remains limited. Using colorectal cancer (CRC) as a model, we developed a machine learning (ML) framework, CANDiT ( Cancer Associated Nodes for Differentiation Targeting ), to selectively induce differentiation and death of cancer stem cells (CSCs)—a key obstacle to du...

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Literature Corpus work
abbc8ca0-3110-5ea7-92c2-22757a177470
DOI
10.1101/2023.09.13.557628
Open publication

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Machine Learning–Guided Differentiation Therapy Targets Cancer Stem Cells in Colorectal CancersDOI 10.1101/2023.09.13.557628
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