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Constructing a cancer stem cell related prognostic model for predicting immune landscape and drug sensitivity in colorectal cancer

12 Jun 2023

Abstract excerpt

Background: Colorectal cancer (CRC) ranks the second malignancy with high incidence and mortality worldwide. Cancer stem cells (CSCs) function critically in cancer progression and metastasis via the interplay with immune cells in tumor microenvironment. This study aimed to identify important CSC marker genes and parsed the role of these marker genes in CRC. Materials and methods: CRC samples’ single-cell RNA...

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PMID: 37377935
DOI: 10.3389/fphar.2023.1200017

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