Article

Conventional therapy induces tumor immunoediting and modulates the immune contexture in colorectal cancer

2024-08-21

Abstract excerpt

<h4>Background</h4> Cancer immunotherapies for patients with colorectal cancer (CRC) continue to lag behind other solid cancer types with the exception of 4% of patients with microsatellite-instable tumors. Thus, there is an urgent need to broaden the clinical benefit of checkpoint blockers to CRC by combining conventional therapies to sensitise tumors to immunotherapy. However, the impact of conventional drugs o...

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Literature Corpus work: cb51dd66-2a30-5cf4-9453-5c86da55e995
DOI: 10.1101/2024.08.21.608938

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