Back to search

Article

Developmental changes and metabolic reprogramming during establishment of infection and progression of <i>Trypanosoma brucei brucei</i> through its insect host

2021-05-26

Abstract excerpt

<h4>ABSTRACT</h4> Trypanosoma brucei ssp., unicellular parasites causing human and animal trypanosomiasis, are transmitted between mammals by tsetse flies. Periodic changes in variant surface glycoproteins (VSG), which form the parasite coat in the mammal, allow them to evade the host immune response. Different isolates of T. brucei show heterogeneity in their repertoires of VSG genes and have single nucleotide...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5ac9efc0-9a32-5f81-a0d2-fe96336f670c
DOI
10.1101/2021.05.26.445766
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Developmental changes and metabolic reprogramming during establishment of infection and progression of <i>Trypanosoma brucei brucei</i> through its insect hostDOI 10.1101/2021.05.26.445766
Developmental changes and metabolic reprogramming during establishment of infection and progression of Trypanosoma brucei brucei through its insect hostSemantic proximity
Transcriptome Profiling of Trypanosoma brucei Development in the Tsetse Fly Vector Glossina morsitansSemantic proximity
Transcriptomic analysis reveals metabolic switches and surface remodeling as key processes for stage transition in <i>Trypanosoma cruzi</i>Semantic proximity
Single-cell transcriptomics reveals expression profiles of <i>Trypanosoma brucei</i> sexual stagesSemantic proximity
RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stagesSemantic proximity
The Genome of the African Trypanosome <i>Trypanosoma brucei</i>Semantic proximity
The <i>Trypanosoma cruzi</i> cell atlas; a single-cell resource for understanding parasite population heterogeneity and differentiationSemantic proximity
vsgseq2: an updated pipeline for analysis of the diversity and abundance of population-wide <i>Trypanosoma brucei</i> VSG expressionSemantic proximity
Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stagesSemantic proximity
Genome Sequence of the Tsetse Fly ( <i>Glossina morsitans</i> ): Vector of African TrypanosomiasisSemantic proximity
Transcriptomic analysis reveals metabolic switches and surface remodeling as key processes for stage transition in Trypanosoma cruziSemantic proximity
The Glossina Genome Cluster: Comparative Genomic Analysis of the Vectors of African TrypanosomesSemantic proximity
Select a neighboring publication to make it the new centre.