Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental changes and metabolic reprogramming during establishment of infection and progression of Trypanosoma brucei brucei through its insect host

20 Sept 2021

Abstract excerpt

Trypanosoma brucei ssp., unicellular parasites causing human and animal trypanosomiasis, are transmitted between mammals by tsetse flies. Periodic changes in variant surface glycoproteins (VSG), which form the parasite coat in the mammal, allow them to evade the host immune response. Different isolates of T. brucei show heterogeneity in their repertoires of VSG genes and have single nucleotide polymorphisms and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biochemical and Molecular Research
Share to Insect symbiosis and bacterial influences
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34543277
DOI: 10.1371/journal.pntd.0009504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental changes and metabolic reprogramming during establishment of infection and progression of Trypanosoma brucei brucei through its insect hostPMID 34543277Read ↗

Developmental changes and metabolic reprogramming during establishment of infection and progression of <i>Trypanosoma brucei brucei</i> through its insect hostSemantic proximity Read ↗

Transcriptome Profiling of Trypanosoma brucei Development in the Tsetse Fly Vector Glossina morsitansSemantic proximity Read ↗

The Genome of the African Trypanosome <i>Trypanosoma brucei</i>Semantic proximity Read ↗

Single-cell transcriptomics reveals expression profiles of Trypanosoma brucei sexual stagesSemantic proximity Read ↗

RNA-Seq analysis validates the use of culture-derived Trypanosoma brucei and provides new markers for mammalian and insect life-cycle stagesSemantic proximity Read ↗

The proteome and transcriptome of the infectious metacyclic form of Trypanosoma brucei define quiescent cells primed for mammalian invasionSemantic proximity Read ↗

High-resolution analysis of multi-copy variant surface glycoprotein gene expression sites in African trypanosomesSemantic proximity Read ↗

Transcriptomic analysis reveals metabolic switches and surface remodeling as key processes for stage transition in Trypanosoma cruziSemantic proximity Read ↗

African trypanosomes: the genome and adaptations for immune evasionSemantic proximity Read ↗

Trypanosomatid comparative genomics: contributions to the study of parasite biology and different parasitic diseasesSemantic proximity Read ↗

Genomics of Trypanosomatidae: Where We Stand and What Needs to Be Done?Semantic proximity Read ↗

Single-cell RNA sequencing of Trypanosoma brucei from tsetse salivary glands unveils metacyclogenesis and identifies potential transmission blocking antigensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.