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Discovery and Genetic Validation of Chemotherapeutic Targets for Chagas' Disease

7 Jan 2019

Abstract excerpt

There is an urgent need to develop new treatments for Chagas´ disease. To identify drug targets, it is important to understand the basic biology of Trypanosoma cruzi, in particular with respect to the biological pathways or proteins that are essential for its survival within the host. This review provides a streamlined approach for identifying drug targets using freely available chemogenetic databases and...

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PMID: 30666299
DOI: 10.3389/fcimb.2018.00439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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