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Article

Genetic profiling of the isoprenoid and sterol biosynthesis pathway genes of Trypanosoma cruzi.

PloS one - 1 Jan 2014

Cosentino Raúl O, Agüero Fernán

Abstract excerpt

In Trypanosoma cruzi the isoprenoid and sterol biosynthesis pathways are validated targets for chemotherapeutic intervention. In this work we present a study of the genetic diversity observed in genes from these pathways. Using a number of bioinformatic strategies, we first identified genes that were missing and/or were truncated in the T. cruzi genome. Based on this analysis we obtained the complete sequence of...

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Identifiers

PMID: 24828104
DOI: 10.1371/journal.pone.0096762
PMCID: PMC4020770

Genes

SMO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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