Article

Detecting haplotype-specific transcript variation in long reads with FLAIR2

2023-06-12

Abstract excerpt

<h4>Background</h4> RNA-Seq has brought forth significant discoveries regarding aberrations in RNA processing, implicating these RNA variants in a variety of diseases. Aberrant splicing and single nucleotide variants in RNA have been demonstrated to alter transcript stability, localization, and function. In particular, the upregulation of ADAR, an enzyme which mediates adenosine-to-inosine editing, has been previ...

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Literature Corpus work: aad4a869-1ec1-50d3-9cc2-3add0b099c6b
DOI: 10.1101/2023.06.09.544396

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