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Polygenic score for sleep duration in relation to risk of Alzheimer’s disease: results from the UK Biobank

2022-12-16

Abstract excerpt

<h4>INTRODUCTION</h4> Studies have suggested sleep duration may be associated with Alzheimer’s disease risk, but findings based on self-reported sleep duration are likely to be influenced by reverse causation and residual confounding bias. <h4>METHODS</h4> A polygenic score (PGS) for device-measured sleep duration was constructed using LDpred2-auto in 77,770 white British UK Biobank participants. We applied the PG...

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Literature Corpus work
aac21310-99f9-5f2b-97e6-639f36b60c4c
DOI
10.1101/2022.12.15.22283413
Open publication

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Polygenic score for sleep duration in relation to risk of Alzheimer’s disease: results from the UK BiobankDOI 10.1101/2022.12.15.22283413
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