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Article

Polygenic risk score identifies associations between sleep duration and diseases determined from an electronic medical record biobank

5 Dec 2018

Abstract excerpt

STUDY OBJECTIVES: We aimed to detect cross-sectional phenotype and polygenic risk score (PRS) associations between sleep duration and prevalent diseases using the Partners Biobank, a hospital-based cohort study linking electronic medical records (EMR) with genetic information. METHODS: Disease prevalence was determined from EMR, and sleep duration was self-reported. A PRS for sleep duration was derived using 78...

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PMID: 30521049
DOI: 10.1093/sleep/zsy247

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