Article

Discovering the genetic architecture of sleep regulation: genome-wide association study of device-measured sleep traits.

2025-07-17

Abstract excerpt

Sleep is essential for health and regulated by genetic and environmental factors. We performed genome-wide association studies of device-measured sleep duration, efficiency, and REM/NREM phases in 80,013 UK Biobank participants using accelerometer measurements separately validated against polysomnography. We identified 20 autosomal loci, 12 of which were novel, and report the first genome-wide significant signals...

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Literature Corpus work: b6f7679b-86f6-5333-afd4-8a8a1dc0116e
DOI: 10.1101/2025.07.17.25331692

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