Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sleep Duration Polygenic Risk and Phenotype: Associations with Biomarkers of Accelerated Aging in the Baltimore Longitudinal Study of Aging.

International journal of aging & human development - 1 Mar 2025

Sosnowski David W, Smail Emily J, Maher Brion S, Moore Ann Zenobia, Kuo Pei-Lun, Wu Mark N, Low Dominique V, Stone Katie L, Simonsick Eleanor M, Ferrucci Luigi, Spira Adam P

Abstract excerpt

We sought to explore whether genetic risk for, and self-reported, short sleep are associated with biological aging and whether age and sex moderate these associations. Participants were a subset of individuals from the Baltimore Longitudinal Study of Aging who had complete data on self-reported sleep (n = 567) or genotype (n = 367). Outcomes included: Intrinsic Horvath age, Hannum age, PhenoAge, GrimAge, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Baltimore

Share to Biomarkers

Share to Longitudinal Studies

Share to Multifactorial Inheritance

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 38347745
DOI: 10.1177/00914150241231192
PMCID: PMC11317550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sleep Duration Polygenic Risk and Phenotype: Associations with Biomarkers of Accelerated Aging in the Baltimore Longitudinal Study of Aging.PMID 38347745Read ↗

Evaluating the nonlinear effects of sleep duration on biological aging across phenotypic, genomic, and epigenomic data.Semantic proximity Read ↗

Combined effects of genetic predisposition and sleep quality on acceleration of biological ageing: Findings from the UK biobank cohort.Semantic proximity Read ↗

Sleep chart of biological aging clocks across organs and omicsSemantic proximity Read ↗

Role of sleep quality in the acceleration of biological aging and its potential for preventive interaction on air pollution insults: findings from the UK Biobank cohortSemantic proximity Read ↗

Causal associations of short and long sleep durations with 12 cardiovascular diseases: linear and nonlinear Mendelian randomization analyses in UK Biobank.Semantic proximity Read ↗

Sleep patterns, genetic susceptibility, and incident cardiovascular disease: a prospective study of 385 292 UK biobank participants.Semantic proximity Read ↗

Poor sleep is robustly correlated with accelerated aging but the evidence for causation is mixedSemantic proximity Read ↗

Epigenetic age acceleration and prevalent age- related neurological disorders: a two-sample Mendelian randomization studySemantic proximity Read ↗

Sleep traits causally affect epigenetic age acceleration: a Mendelian randomization studySemantic proximity Read ↗

Polygenic risk score identifies associations between sleep duration and diseases determined from an electronic medical record biobankSemantic proximity Read ↗

Genetic and non-genetic factors associated with the phenotype of exceptional longevity & normal cognition.Semantic proximity Read ↗

Polygenic score for sleep duration in relation to risk of Alzheimer’s disease: results from the UK BiobankSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.