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Evaluation of a tetravalent DNA vaccine against dengue : integrating biochemical studies on dengue virus envelope protein to a domain-based antigen design

2017-01-01

Abstract excerpt

Dengue virus (DENV) is among the most important mosquito-borne human pathogens worldwide. Concerns regarding the effectiveness of Dengue vaccines together with emergence of Zika virus (ZIKV) have reignited the interest for new vaccines using alternative approaches. Given that the envelope glycoprotein (E) is the main target of neutralizing antibodies, it has been used as the antigen of choice for vaccine developme...

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Literature Corpus work
aaac51bb-5efa-5208-8f79-7d79207fe717
DOI
10.21954/ou.ro.0000bfaf
Open publication

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Evaluation of a tetravalent DNA vaccine against dengue : integrating biochemical studies on dengue virus envelope protein to a domain-based antigen designDOI 10.21954/ou.ro.0000bfaf
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