Article

Causal inference in cancer epidemiology: what is the role of Mendelian randomization?

2017-11-28

Abstract excerpt

Observational epidemiological studies are prone to confounding, measurement error, and reverse causation, undermining their ability to generate reliable causal estimates of the effect of risk factors to inform cancer prevention and treatment strategies. Mendelian randomization (MR) is an analytical approach that uses genetic variants to proxy potentially modifiable exposures (e.g. environmental factors, biological...

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Literature Corpus work: aa97b0d0-9835-52ac-b09c-d7c3a41bfc38
DOI: 10.1101/223966

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