Article
Systematic review of Mendelian randomization studies on risk of cancer.
BMC medicine - 2 Feb 2022
Markozannes Georgios, Kanellopoulou Afroditi, Dimopoulou Olympia, Kosmidis Dimitrios, Zhang Xiaomeng, Wang Lijuan, Theodoratou Evropi, Gill Dipender, Burgess Stephen, Tsilidis Konstantinos K
Abstract excerpt
BACKGROUND: We aimed to map and describe the current state of Mendelian randomization (MR) literature on cancer risk and to identify associations supported by robust evidence. METHODS: We searched PubMed and Scopus up to 06/10/2020 for MR studies investigating the association of any genetically predicted risk factor with cancer risk. We categorized the reported associations based on a priori designed levels of...
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