Article

An ATP-Binding Cassette Transporter Gene Links Innate and Adaptive Immune Responses

2024-01-02

Abstract excerpt

Positive-strand RNA viruses and DNA viruses generate double-stranded RNA (dsRNA) during their replication processes and innate immune responses against viral infections are orchestrated by numerous interferon-stimulating genes, yet the detailed coordination of downstream signaling of anti-viral immune responses is not fully understood. Recent studies suggest 2’-5’- Oligoadenylate Synthetase 1 (OAS1) may have a pro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: aa6a08a8-cb56-5c90-b4a2-3d4cd1a73485
DOI: 10.1101/2023.12.31.573785

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An ATP-Binding Cassette Transporter Gene Links Innate and Adaptive Immune ResponsesDOI 10.1101/2023.12.31.573785Read

ABCF1 regulates dsDNA-induced immune responses in human airway epithelial cellsSemantic proximity Read

Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases.Semantic proximity Read

ATP-dependent transporters: emerging players at the crossroads of immunity and metabolismSemantic proximity Read

Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene.Semantic proximity Read

Distinct Antiviral Roles for Human 2′,5′-Oligoadenylate Synthetase Family Members against Dengue Virus InfectionSemantic proximity Read

Identification of Novel Host Cell Binding Partners of Oas1b, the Protein Conferring Resistance to Flavivirus-Induced Disease in MiceSemantic proximity Read

ATP-binding cassette transporters are required for efficient RNA interference in Caenorhabditis elegans.Semantic proximity Read

Orthogonal genome-wide screenings in bat cells identify MTHFD1 as a target of broad antiviral therapySemantic proximity Read

Mitochondrial localization of the OAS1 p46 isoform associated with a common single nucleotide polymorphism.Semantic proximity Read

Delineating the Role of Aedes aegypti ABC Transporter Gene Family during Mosquito Development and Arboviral Infection via Transcriptome AnalysesSemantic proximity Read

Innate resistance to flavivirus infections and the functions of 2'-5' oligoadenylate synthetases.Semantic proximity Read

Endomembrane targeting of human OAS1 p46 augments antiviral activity.Semantic proximity Read