Article

Orthogonal genome-wide screenings in bat cells identify MTHFD1 as a target of broad antiviral therapy

2020-03-30

Abstract excerpt

<h4>SUMMARY</h4> Bats are responsible for the zoonotic transmission of several major viral diseases including the 2003 SARS outbreak and the ongoing COVID-19 pandemic. While bat genomic sequencing studies have revealed characteristic adaptations of the innate immune system, functional genomic studies are urgently needed to provide a foundation for the molecular dissection of the tolerance of viral infections in b...

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Literature Corpus work: a629c367-8899-56eb-8d03-5c9df277db69
DOI: 10.1101/2020.03.29.014209

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