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Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases.

Experimental & molecular medicine - 6 Mar 2015

Choi Un Yung, Kang Ji-Seon, Hwang Yune Sahng, Kim Young-Joon

Abstract excerpt

The study of antiviral pathways to reveal methods for the effective response and clearance of virus is closely related to understanding interferon (IFN) signaling and its downstream target genes, IFN-stimulated genes. One of the key antiviral factors induced by IFNs, 2'-5' oligoadenylate synthase (OAS), is a well-known molecule that regulates the early phase of viral infection by degrading viral RNA in...

Topics

2',5'-Oligoadenylate Synthetase
Animals
Biomarkers
Disease Susceptibility
Endoribonucleases
Genetic Predisposition to Disease
Humans
Multigene Family
Polymorphism, Single Nucleotide
Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25744296
DOI: 10.1038/emm.2014.110
PMCID: PMC4351405

Genes

OASL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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