Article
Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases.
Experimental & molecular medicine - 6 Mar 2015
Choi Un Yung, Kang Ji-Seon, Hwang Yune Sahng, Kim Young-Joon
Abstract excerpt
The study of antiviral pathways to reveal methods for the effective response and clearance of virus is closely related to understanding interferon (IFN) signaling and its downstream target genes, IFN-stimulated genes. One of the key antiviral factors induced by IFNs, 2'-5' oligoadenylate synthase (OAS), is a well-known molecule that regulates the early phase of viral infection by degrading viral RNA in...
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