Article

Ellagic acid produces neuroprotection against LPS-induced dopamine neurotoxicity via the inhibition of microglial NLRP3 inflammasome activation

2019-11-27

Abstract excerpt

<h4>Background: </h4> Neuroinflammation plays a crucial role in the pathological process of Parkinson's disease (PD). Nod-like receptor protein 3 (NLRP3) inflammasome was highly located in microglia and involved in the process of neuroinflammation. Activation of NLRP3 inflammasome has been confirmed to contribute to the progression of PD. Thus, inhibition of NLRP3 inflammasomes activation could be an important bre...

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Literature Corpus work: aa3dfb74-1a61-5323-96c6-9beff9057bbd
DOI: 10.21203/rs.2.17707/v1

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