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Combined neuroprotective potential of Levodopa and Resveratrol to ameliorates cognitive impairments in rotenone-induced Parkinson's disease via targeting TLR mediated neuroinflammation

2023-08-23

Abstract excerpt

<h4>Background: </h4> and Aim By inducing oxidative stress and hindering mitochondrial activity, rotenone can cause neuronal death or cell apoptosis, which is the pathophysiological characteristic of PD. To investigate synergistic effects of levodopa (LD) and resveratrol (RES), a natural polyphenolic molecule, on rotenone-induced toxicity in PD-related cell lines and animal models. Methods The in vitro experiments...

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Literature Corpus work
679ea709-e473-5d3b-9a35-019257fff930
DOI
10.22541/au.169277558.84495740/v1
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