Back to search

Article

Naringenin Ameliorates LPS-Induced Neuroinflammation Through NF-κB Signaling in Human Microglia and Protects Neuronal Cells

2026-01-14

Abstract excerpt

<h4>Background: </h4> Engagement of the NF-κB signaling pathway is crucial for controlling im-mune and inflammatory gene expression within the central nervous system (CNS). Naringenin, a flavonoid derived from citrus fruits, is known for its anti-inflammatory and antioxidant effects; however, its impact on LPS-induced neuroinflammation in HMC3 (human microglial) and SH-SY5Y (neuronal) cell lines has not been thoro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d5c43d37-c57a-574d-8ceb-581e45b5c627
DOI
10.20944/preprints202601.1082.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Naringenin Ameliorates LPS-Induced Neuroinflammation Through NF-κB Signaling in Human Microglia and Protects Neuronal CellsDOI 10.20944/preprints202601.1082.v1
Molecular Mechanisms Underlying Neuroinflammation Intervention with Medicinal Plants: A Critical and Narrative Review of the Current LiteratureSemantic proximity
Farrerol attenuates MPP+‐induced inflammatory response by TLR4 signaling in a microglia cell lineSemantic proximity
Ellagic acid produces neuroprotection against LPS-induced dopamine neurotoxicity via the inhibition of microglial NLRP3 inflammasome activationSemantic proximity
Pharmacological Blocker of NF-κb and Mitochondrial Ros Restrict NLRP3&nbsp;Inflammasome Activation and Rescue Dopaminergic Neurons in Vitro and in Vivo Parkinson’s DiseaseSemantic proximity
Germacrone attenuates memory impairment, hippocampal inflammation, and neurological deficits induced by Lipopolysaccharide in miceSemantic proximity
Ellagic acid produces neuroprotection against LPS-induced dopamine neurotoxicity via the inhibition of microglial NLRP3 inflammasome activationSemantic proximity
Interleukin-37 modulates microglial phenotype and inhibits inflammatory response via the MyD88/NF-κB pathway in Lipopolysaccharide-induced neuroinflammationSemantic proximity
Ellagic acid produces neuroprotection against LPS-induced dopamine neurotoxicity via the inhibition of microglial NLRP3 inflammasome activationSemantic proximity
Naringin ameliorates Alzheimer’s disease-like cognitive impairment through coordinated NF-κB/Nrf2 pathway modulationSemantic proximity
Shikonin attenuates cerebral ischemia/reperfusion injury via inhibiting NOD2/RIP2/NF-κB-mediated microglia polarization and neuroinflammation.Semantic proximity
Camptothecin regulates microglia polarization and exerts neuroprotective effects via the AKT/Nrf2/HO-1-NF-κB signal axis in vivo and in vitroSemantic proximity
Camptothecin regulates microglia polarization and exerts neuroprotective effects via the AKT/Nrf2/HO-1-NF-κB signal axis in vivo and in vitroSemantic proximity
Select a neighboring publication to make it the new centre.