Article

Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis

2024-11-15

Abstract excerpt

<h4>ABSTRACT</h4> Pulmonary fibrosis (PF) is a pathology associated with interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF). Fibrosis promotes continual secretion of extracellular matrix (ECM), producing non-functional scar tissue and causing organ failure. This study investigated the tyrosine kinase receptor Ephrin type-B receptor 4 (EphB4) as a mediator of PF. To this end, we gener...

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Literature Corpus work: 43de7d46-287e-5bd2-a4b5-17376fcfffce
DOI: 10.1101/2024.11.14.622787

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