Article

Harnessing Dietary Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression Management

2025-12-04

Abstract excerpt

Major depressive disorder (MDD) remains a leading cause of disability worldwide, with conventional antidepressants offering incomplete and often transient relief. Mounting ev-idence highlights disturbances in tryptophan (Trp) metabolism as a key biological axis linking inflammation, neuroplasticity, and mood regulation. Plant-derived compounds that modulate this pathway, including 5-hydroxytryptophan, isoflavones,...

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Literature Corpus work: aa1a5d0f-7228-5f17-8021-b9271d530431
DOI: 10.20944/preprints202509.2303.v2

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