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Harnessing Plant-Derived Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression Management

2025-09-29

Abstract excerpt

Major depressive disorder (MDD) remains a leading cause of disability worldwide, with conventional antidepressants offering incomplete and often transient relief. Mounting ev-idence highlights disturbances in tryptophan (Trp) metabolism as a key biological axis linking inflammation, neuroplasticity, and mood regulation. Plant-derived compounds that modulate this pathway, including 5-hydroxytryptophan, isoflavones,...

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Literature Corpus work
25e1daa6-2d4d-5cb3-a378-46da35456c12
DOI
10.20944/preprints202509.2303.v1
Open publication

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Harnessing Plant-Derived Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression ManagementDOI 10.20944/preprints202509.2303.v1
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