Article

Tryptophan metabolism and the gut-brain axis: focus on specific gut microbial genera

2025-07-02

Abstract excerpt

The gut-brain axis (GBA) is a crucial connection that enables bidirectional communication between the central nervous system and gastrointestinal tract. Serotonin is a tryptophan (Trp) metabolite and an important gastrointestinal signaling molecule. Kynurenine and indole derivatives mediate the central nervous system, thereby affecting neurological diseases. The gut microbiota has direct or indirect impact on Trp...

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Literature Corpus work: 95df538c-36bf-58dc-9469-0e1bb6900f74
DOI: 10.1016/j.jfutfo.2024.09.006

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