Article

Common tissue-specific expressions and regulatory factors of c-KIT isoforms with and without GNNK and GNSK sequences across five mammals

2025-08-29

Abstract excerpt

c-KIT is a transmembrane receptor tyrosine kinase involved in various signaling pathways. Alternative pre-mRNA splicing of KIT results in isoforms that differ in the presence or absence of four amino acid sequences in the extracellular juxtamembrane region, such as, isoforms with and without the GNNK sequence (GNNK+ and GNNK−, respectively) in humans and mice, and those with and without GNSK (GNSK+ and GNSK−, res...

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Literature Corpus work: aa13aa82-6dc2-5d05-96f9-f883bc668463
DOI: 10.1101/2025.08.25.672062

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