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Two Receptors, Two Isoforms, Two Cancers: Comprehensive Analysis of KIT and TrkA Expression in Neuroblastoma and Acute Myeloid Leukemia

18 Oct 2019

Abstract excerpt

Pediatric cancers represent a wide variety of different tumors, nonetheless they have unique features that distinguish them from adult cancers. Receptor tyrosine kinases KIT and TrkA functions in AML and NB respectively are well characterized. Nevertheless, expression of these receptors is found in both tumors, little is known about KIT function in NB and TrkA – in AML. By combining gene enrichment analysis with...

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PMID: 31681584
DOI: 10.3389/fonc.2019.01046

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