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Article

Normal and oncogenic forms of the receptor tyrosine kinase kit.

Stem cells (Dayton, Ohio) - 1 Jan 2005

Lennartsson Johan, Jelacic Tanya, Linnekin Diana, Shivakrupa R

Abstract excerpt

Kit is a receptor tyrosine kinase (RTK) that binds stem cell factor. This receptor ligand combination is important for normal hematopoiesis, as well as pigmentation, gut function, and reproduction. Structurally, Kit has both an extracellular and intracellular region. Theintra-cellular region is comprised of a juxtamembrane domain (JMD), a kinase domain, a kinase insert, and a carboxyl tail. Inappropriate...

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Identifiers

PMID: 15625120
DOI: 10.1634/stemcells.2004-0117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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